Does having a cigarette make you feel more energized and focused? Does having a drink make you feel less depressed, less anxious or help wind down tension at the end of a long day? The reality is, people use substances because they have an effect that they appreciate. The problem for some, however, is that the effect of substances is inherently short term. Once the effect has passed, you may find that you want to feel those effects again because the underlying state of being is uncomfortable in some way.